Robust estimators for expression analysis
نویسندگان
چکیده
منابع مشابه
Robust estimators for expression analysis
MOTIVATION We consider the problem of estimating values associated with gene expression from oligonucleotide arrays. Such estimates should linearly track concentration, yield non-negative results, have statistical guarantees of robustness against outliers, and allow estimates of significance and variance. RESULTS A hierarchy of simple models is used to design robust estimators meeting these g...
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This is supplemental data extracted from the paper Robust Estimators for Expression Analysis and provided on this web-site. 1. ON PROPERTIES OF THE SIGNAL ALGORITHM One advantage of using a logarithmic transformation is that it approximately stabilizes the variance of the resulting estimate. This stabilization can be observed in figure 1. Note that as expected, this approximation breaks down at...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2002
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/18.12.1585